renal diseases — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7714	Temocapil		Tyrosinase
	Temocapril is an inhibitor of tyrosine kinase.		Tyrosinase
T6698	Temocapril hydrochloride	CS-622 HCl,Acecol,Temocapril HCl,CS-622	RAAS
	Temocapril hydrochloride (CS-622 HCl), the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension.		RAAS
T50000	2-Iodohippuric Acid		Others
	2-Iodohippuric Acid can be used to measure renal clearance for renal function studies, and for the diagnosis of certain diseases, such as liver and kidney disease. In addition, it is used in the synthesis of certain drug...		Others
T1182	Levocarnitine propionate hydrochloride	Propionyl-L-carnitine hydrochloride,L-Propionylcarnitine chloride,ST-261	Histamine Receptor
	Levocarnitine propionate hydrochloride (ST-261) is used for the treatment of the deterioration of renal function, congestive heart failure, intermittent claudication, and other diseases.		Histamine Receptor
T16808	Runcaciguat		Others , Guanylate cyclase
	Runcaciguat is a soluble guanylate cyclase stimulator. Runcaciguat combines with selective partial adenosine A1 receptor agonists and can be used in studies about cardiovascular and renal diseases.		Others , Guanylate cyclase
T8366	Mitochonic acid 5	MA-5	Mitochondrial Metabolism
	Mitochonic acid 5 (MA-5) is a derivative of the plant hormone indole-3-acetic acid. Mitochonic acid 5 binds mitochondria and ameliorates renal tubular and cardiac myocyte damage.It has been shown to improve survival of f...		Mitochondrial Metabolism
T11412	IPN60090	GLS1-IN-1	Others , transporter
	IPN60090 is a novel, potent, orally bioavailable, renal-type glutaminase (GLS1)-specific inhibitor with an IC50 value of 31 nM for GLS1. IPN60090 has potential anticancer and immunostimulant/immunomodulatory activity, se...		Others , transporter
T8053	N-Acetyl-L-arginine	Ac-Arg-OH	Endogenous Metabolite
	N-Acetyl-L-arginine (Ac-Arg-OH) belongs to the class of organic compounds known as n-acyl-l-alpha-amino acids. These are n-acylated alpha amino acids which have the L-configuration of the alpha-carbon atom. N-a-Acetyl-L-...		Endogenous Metabolite
T39611	Enuvaptan	Enuvaptan,BAY-2327949
	Enuvaptan is a vasopressin receptor antagonist and has the potential for research into renal and cardiovascular diseases.
T71450	Ilacirnon sodium
	Ilacirnon sodium is a potent CCR2 antagonist that may be useful in the treatment of renal diseases including Focal Segmental Glomerulosclerosis and Diabetic Nephropathy.
TN3753	Dalbergioidin		Tyrosinase , ROS , Akt , PI3K , TGF-beta/Smad
	Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces bikiniensis that has commonly been used as an indicator or...		Tyrosinase , ROS , Akt , PI3K , TGF-beta/Smad
T76762	Tabalumab
	Tabalumab (LY2127399), a humanized monoclonal antibody (IgG4 type) targeting B-cell activating factor (BAFF), exhibits neutralizing activity against both membrane-bound and soluble BAFF. This compound is relevant for res...
T70990	ADMA-d6
	NG,NG-dimethyl-L-arginine-d6 (ADMA-d6) (hydrochloride) is intended for use as an internal standard for the quantification of NG,NG-dimethyl-L-arginine by GC- or LC-MS. ADMA is an endogenous inhibitor of nitric oxide synt...